Agentis Air to present study results on Indoor Air Quality Optimization for Effectiveness and Energy Efficiency at the Workplace and Indoor Aerosols Conference May 6-8 in Gaeta, Italy
Rockville, MD, April 30, 2025—Air-purification technology company Agentis Air will share the findings from a new study on “Optimizing the Use of Room Air Purifiers in Combination with HVAC Filters for IAQ and Energy Efficiency for PM2.5 and Ultrafine Particle Removal” in a poster session at the Sixth Workplace and Indoor Aerosols Conference May 6-8, in Gaeta, Italy. Particle Pathways is the theme for WIAC2025, a pioneering three-day international conference designed to explore the critical intersection of indoor air pollution and airborne diseases.
Indoor air quality is increasingly recognized as a serious health hazard in many international environments. In the face of the serious and wide-ranging threat presented by ultrafine particles and poor indoor air quality, HVAC-only solutions—using higher MERV-rated filters—use more energy and require frequent filter changes, making them more expensive to maintain and environmentally unfriendly. As this study demonstrate, using appropriate room air purifiers in tandem with standard HVAC systems can reduce the energy penalty while achieving ultrafine particle filtration goals.
The study tests and directly measures the collective impact on IAQ and energy consumption of air purifiers used in combination with HVAC systems, for removal of fine and ultra-fine particles.
A comparison is also made to HVAC systems operating without auxiliary in-room air purification. The study goal was to identify an optimal balance where superior IAQ can be maintained while ensuring minimal energy usage. In addition, the objective is to understand how this balance is impacted by particle size. Study results indicate a 19-40% improvement in ultrafine particle collection when HVAC systems are supplemented by appropriate in-room air purifiers.

Agentis Air president Larry Rotehnberg will be delivering the research findings. The study has added relevance considering the new ASHRAE Standard 241: Control of Infectious Aerosols, which establishes an equivalent clean airflow (ECAi) formula that includes the use of room air purifiers, as a supplement to HVAC systems, and to outside ventilation, to remove fine and ultrafine particles including aerosolized viruses and wildfire smoke.
About Agentis Air
Agentis Air is a collaboration of scientists, engineers, and air-quality experts on a mission to improve health and longevity with innovative indoor air quality solutions. With decades of university research and development experience, the company’s focus is on transformational technologies as the foundation for more effective air-purification products. The Agentis Air research and development team is led by a scientist with over 100 patents and 20 years of experience in advanced air-purification technologies. Brio 650, an ASHRAE Standard 241-compliant, zero-ozone, and low noise in-room air purifier was used in this study.
To learn more about this study, contact Agentis Air Larry Rothenberg: lrothenberg@agentisair.com
About WIAC
Workplace & Indoor Aerosols Conference is a well-established conference series with a science orientation, WIAC attracts researchers and other professionals from the fields of indoor air quality, built environments, HVAC, health sciences, public health policy, chemistry, biology, psychology, urban planning, mechanical engineering, architecture, and building design and management to discuss the latest scientific advances and ongoing research in the field. WIAC conferences are organized every two years as international events. https://www.wiac2025.eu
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